HORDB

ID: hor006635
Uniprot ID: P51917
Protein name: GnRH-associated peptide 3
Gene name: gnrh3
Organism: Carassius auratus (Goldfish)
Family: GnRH family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Carassius (genus), Cyprininae (subfamily), Cyprinidae (family), Cyprinoidei (suborder), Cypriniformes (order), Cypriniphysae (superorder), Otophysi, Ostariophysi (subcohort), Otomorpha (cohort), Clupeocephala, Osteoglossocephalai, Teleostei (infraclass), Neopterygii (subclass), Actinopteri (class), Actinopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region; GO:0005615 extracellular space

Sequence: SVGEVEATFRMMDSGDAVLSIPMDSPMERLSPIHIVSEVDAEGLPLKEQRFPNRRGRD
Length: 58
Propeptide: MEGKGRVLVQLLMLACVLEVSLCQHWSYGWLPGGKRSVGEVEATFRMMDSGDAVLSIPMDSPMERLSPIHIVSEVDAEGLPLKEQRFPNRRGRD
Signal peptide: MEGKGRVLVQLLMLACVLEVSLC
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor006635_AF2.pdb

hor006635_ESM.pdb

Mass:	748719	Formula:	C276H449N81O90S4
Absent amino acids:	CWY	Common amino acids:	ERSDPV
pI:	4.46	Basic residues:	8
Polar residues:	12	Hydrophobic residues:	17
Hydrophobicity:	-45.52	Boman Index:	-14015
Half-Life:	1.9 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	77.24
Instability Index:	5327.07	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 8729938
Title: Expression of salmon gonadotropin-releasing hormone (GnRH) and chicken GnRH-II precursor messenger ribonucleic acids in the brain and ovary of goldfish.